Gabriele Jovtchev

Personal information

Contacts

Division of Environmental Mutagenesis and Genetic Risk Assessments, Institute of Biodiversity and Ecosystem Research (IBER), BAS, 2 Gagarin Street, 1113 Sofia, Bulgaria,
e-mail: gjovtchev@yahoo.de
phone: 0035 92 8717195/108
fax: 0035 92 8705498

Curriculum vitae

Name: Gabriele Jovtchev
Birth: 24. 09. 1956 in Kleinmachnow, Germany
Nationality: Austrian
Marital Status: married

Education
- 1963 till 1973: 30th Grammar school, Berlin Karlshorst, Germany
- 1982: MSc, Faculty of Biology, Humboldt University of Berlin
- 2001: PhD, Central Laboratory of General Ecology, BAS; thesis: "Investigation of the adaptive response of root tip meristem cells of Hordeum vulgare in vivo – defense reactions against chromatid aberration induction by the herbizide maleic hydrazide"
Employment:
- 1984-1990: Biologist, Institute of Genetics, BAS
- 1990-1996: Biologist and Research Fellow (1991) Institute of Ecology, BAS
- 1996-2007: Research Fellow, Central Laboratory of General Ecology, BAS
- 2007-present: Associate Professor, Central Laboratory of General Ecology, BAS

Research interests

- Cytogenetics, molecular genetics, Hordeum vulgare, Arabidopsis thaliana
- Environmental mutagenesis, genetic ecotoxicology, adaptive response
- Epigenetics, evolution of histone methylation marks
- Karyotype evolution
- Genetic Monitoring

Publications

In journals with impact factor
1. Jovtchev, G., Menke, M., Schubert, I. The comet assay detects adaptation to MNU-induced DNA damage in barley. Mutation Research, 493, Elsevier, 2001, ISSN: 1383-5718, DOI: 10.1016/S1383-5718(01)00166-8, 95 - 100. ISI IF:2.375
2. Jovtchev, G., Stergios, M., Schubert, I. A comparison of N-methyl-N-nitrosourea-induced chromatid aberrations and micronuclei in barley meristems using FISH techniques. Mutat. Res. Genet. Toxicol. Environm. Mutagen. 517, Elsevier, 2002, ISSN: 1383-5718, DOI:10.1016/S1383-5718(02)00038-4, 47 - 51. ISI IF:1.636
3. Schubert, I., Pecinka, A., Meister, A., Klatte, M., Jovtchev, G. DNA damage processing and aberration formation in plants. Cytogenet Genome Res, 104, Karger, 2004, ISSN: 1424-8581 (Print) e-ISSN: 1424-859X, DOI: 10.1159/000077473, 104 - 108. ISI IF:0.497
4. Nikolova, T., Czyz, J., Rolletschek, A., Blysczuk, P., Fuchs, J., Jovtchev, G., Chuderer, S., Kuster, N., Wobus, A. Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neutral progenitor cells. FASEB Journal, 19, 22, Federation of American Societies for Experimental Biology, 2005, ISSN: 0892-6638 Print, 1530-6860 Online, DOI:10.1096/fj.1530-6860, 1686 - 1688. ISI IF:7.064
5. Jovtchev, G., Schubert, V., Meister, A., Barow, M., Schubert, I. Nuclear DNA content and nuclear and cell volume are positively correlated in angiosperms. Cytogenetic and Genome Research, 114, 1, Karger, 2006, ISSN: 1424-8581 (Print); 1424-859X (Electronic), DOI:10.1159/000091932, 77 - 82. ISI IF:1.993
6. Jovtchev, G., Barow, M., Meister, A., Schubert, I. Impact of environmental and endogenous factors on endopolyploidization in angiosperms. Environmental and Experimental Botany, 60, Elsevier, 2007, ISSN: 0098-8472, 404 - 411. ISI IF:1.81
7. Adoukonou-Sagbadja, H., Schubert, V., Dansi, A., Jovtchev, G., Meister, A., Pistrick, K., Akpagana, K., Friedt, W. Flow cytometric analysis reveals different nuclear DNA contents in cultivated Fonio (Digitaria spp.) and some wild relatives from West-Africa. Plant Systematics and Evolution, 267, (1-4), Springer, 2007, ISSN: 0378-2697 (Print) 2199-6881 (Online), DOI:10.1007/s00606-007-0552-z, 163 - 176. ISI IF:1.492
8. Fuchs, J., Jovtchev, G., Schubert, I. The chromosomal distribution of histone methylation marks in gymnosperms differs from that of angiosperms. Chromosome Research, 16, Springer, 2008, ISSN: 0967-3849 (Print) 1573-6849 (Online), DOI: 10.1007/s10577-008-1252-4, 891 - 898. ISI IF:3.405
9. Jovtchev, G., Watanabe, K., Pecinka, A., Rosin, F., Mette, F., Lam, E., Schubert, I. Size and number of tandem repeat arrays can determine somatic homologous pairing of transgene loci mediated by epigenetic modifications in Arabidopsis thaliana nuclei.. Chromosoma, 117, Springer, 2008, ISSN: 0009-5915 (print version) ISSN: 1432-0886 (electronic version), DOI:10.1007/s00412-007-0146-0, 267 - 276. ISI IF:5.111
10. Jovtchev, G., Gateva, S., Stergios, M., Kulekova, S. Cytotoxic and genotoxic effects of paraquat in Hordeum vulgare and human lymphocytes in vitro. Environmental Toxicology, 25, 3, Wiley, 2010, ISSN: 1522-7278, DOI:10.1002/TOX.20503, 294 - 303. ISI IF:1.831
11. Jovtchev, G., Borisova, B., Kuhlmann, M., Fuchs, J., Watanabe, K., Schubert, I., Mette, F. Pairing of lacO tandem repeats in Arabidopsis thaliana nuclei requires the presence of hyper-methylated, large arrays at two chromosomal positions, but does not depend on H3-lysine-9-dimethylation. Chromosoma, 120, Springer, 2011, ISSN: 0967-3849 (Print) 1573-6849 (Online), DOI:10.1007/s00412-011-0335-8., 609 - 619. ISI IF:3.847
12. Kopaskova, M., Hadjo, L., Yankulova, B., Jovtchev, G., Galova, E., Sevcovikova, A., Mukacji, P., Miadocova, E., Bryant, P., Chankova, S. Extract of Lillium candidum L. can modulate the genotoxicity of the antibiotic zeocin.. Molecules, 17, 1, MDPI AG, 2012, ISSN:1420-3049, DOI:10.3390/molecules17010080, 80 - 97. ISI IF:2.095
13. Gateva, S., Jovtchev, G., Stergios, M., Yonova, P. The potential of synthetic thiourea compound to reduce the cytotoxic and genotoxic effects of paraquat in Hordeum vulgare and cultured human lymphocytes.. Environmental Toxicology, 227, 4, Wiley, 2012, ISSN:1522-7278, DOI:10.1002/tox.20633, 220 - 228. ISI IF:2.708
14. Gateva, S., Mitrovska, Z., Jovtchev, G., Chankova, S. Green algae can modulate the genotoxic action of cadmium in human lymphocytes. Biotechnology&Biotechnology Equipment, 26, 1, Taylor & Francis Group, 2012, ISSN: 1310-2818 (Print), 1314-3530 (Online), DOI:10.5504/BBEQ.2011.0149, 2737 - 2742. ISI IF:0.41
15. Gateva, S., Jovtchev, G., Stergios, M. Cytotoxic and clastogenic activity of CdCl2 in human lymphocytes from different donors.. Environmental Toxicology and Pharmacology, 36, 1, Elsevier, 2013, ISSN:1382-668, DOI:10.1016/j.etap.2013.03.021. Epub 2013, 223 - 230. ISI IF:2.205
16. Gateva, S., Jovtchev, G., Stankov, A., Gregan, F. Antigenotoxic capacity of Papaver rhoeas L. extract.. International Journal of Pharmacy and Pharmaceutical Sciences, 6, 1, Innovare Academic Sci. Pvt. Ltd, 2014, ISSN: 0975 - 1491, 717 - 723. ISI IF:1.59
17. Gateva, S., Jovtchev, G., Stankov, A., Gregan, F. Salvia extract can decrease DNA damage induced by zeocin. International Journal of Pharma Medicine and Biological Sciences, 4, 1, Engineering and Technology Publishing, 2015, ISSN:2278-5221, DOI:10.12720/ijpmbs.4.1.1-10, 1 - 10. SJR:0.44
18. Tran, T.D., Cao, H.X., Jovtchev, G., Novak, P., Vu, G.T.H., Macas, J., Schubert, I., Fuchs, J. Chromatin organization and cytological features of carnivorous Genlisea species with large genome size differences. Frontiers in Plant Science, 2015, ISSN:1664-462X, DOI:10.3389/fpls.2015.00613, 1 - 10. ISI IF:3.948
19. Tran, T.D., Chao, H.X., Jovtchev, G., Neumann, P., Novak, P., Fojtova, M., Vu, G.T.H., Macas, J., Fajkus, ,J., Schubert, I., Fuchs, J. Centromere and telomere sequence alterations reflect the rapid genome evolution within the carnivorous plant genus Genlisea. The Plant Journal, 84, 6, Wiley, 2015, ISSN: 1365-313X, DOI:10.1111/tpj.13058, 1087 - 1099. ISI IF:5.972
20. Vu, G.T.H., Schmutzer, T., Bull, F., Cao, H.X., Fuchs, J., Tran, T.D., Jovtchev, G., Pistrick, K., Stein, N., Pecinka, A., Neumann, P., Novak, P., Macas, J., Dear, P.H., Blattner, F.R., Scholz, U., Schubert, I. Comparative Genome Analysis Reveals Divergent Genome Size Evolution in a Carnivorous Plant Genus. The Plant Genome, 8, 3, Crop Science Society of America, 2015, ISSN: 1365-313X, DOI:10.3835/plantgenome2015.04.0021, 1 - 14. ISI IF:3.933
21. Jovtchev, G., Gateva, S., Stankov, A. Lilium compounds kaempferol and jatropham can modulate cytotoxic and genotoxic effects of radiomimetic zeocin in plants and human lymphocytes in vitro. Environmental Toxicology, 31, 6, Wiley, 2016, ISSN: 1522-7278, DOI:10.1002/tox.22088, 751 - 764. ISI IF:3.197
22. Jovtchev, G., Stankov, A., Georgieva, A., Dobreva, A., Bakalova, R., Aoki, I., Mileva, M. Cytotoxic and genotoxic potential of Bulgarian Rosa alba L. essential oil – in vitro model study. Biotechnology & Biotechnological Equipment, 32, 2, Taylor & Francis, 2018, ISSN: 1310-2818, eISSN: 1314-3530, DOI:10.1080/13102818.2017.1423245, 513-518. ISI IF: 1.227 С ISI IF - Q4
23. Gateva, S., Jovtchev, G., Stankov, A., Georgieva, A., Dobreva, A., Mileva, M. The potential of geraniol to reduce cytotoxic and genotoxic effects of MNNG in plant and human lymphocyte test-systems. South African Journal of Botany, 123, Elsevier, 2019, ISSN: 0254-6299, DOI:10.1016/j.sajb.2019.03.005, 170-179. ISI IF: 1.442 С ISI IF - Q2
24. Jovtchev, G., Stankov, A., Ravnachka, I., Gateva, S., Dimitrov, D., Tyutyundzhiev, N., Nikolova, N., Angelov, Ch. How can the natural radiation background affect DNA integrity in angiosperm plant species at different altitudes in Rila Mountain (South-West Bulgaria)? Environmental Science and Pollution Research, Springer, 2019, ISSN: 0944-1344, eISSN: 1614-7499, DOI: 10.1007/s11356-019-04872-1, ISI IF: 2.8 С ISI IF - Q2
25. Gateva, S., Jovtchev, G., Stankov, A. Direct Treatment with Roundup vs. Treatment with Plant Extract Previously Influenced by Roundup: Does the Genotoxic Effect Differ? Българска академия на науките, Издателство на БАН „Проф. Марин Дринов“, приета за печат: 2018, ISSN: 1310–1331 (Print), ISSN 2367–5535 (Online), SJR: 0.21, ISI IF: 0.27 С ISI IF - Q4
26. Gateva, S., Jovtchev, G., Stankov, A. Geraniol inhibits the genotoxic effect of MNNG in plant and human lymphocyte test-systems. Compt. Rend Acad. Bulg. Sci., проф. Марин Дринов, приета за печат: 2018, ISSN: 1310–1331, SJR: 0.21, ISI IF: 0.27 С ISI IF - Q4
27. Jovtchev, G., Stankov, A. Anticlastogenic potential of Origanum vulgare L. extract. Comptes rendus de l’Académie bulgare des Sciences, Prof. Marin Drinov” Publishing House of BAS, приета за печат: 2019, ISSN: 1310–1331 (Print) ISSN 2367–5535 (Online), ISI IF: 0.27 С ISI IF – Q4
In journals without impact factor
28. Rieger, R., Michaelis, A., Jovtchev, G., Nikolova, T. Copper sulfate and lead nitrate pretreatments trigger "adaptive responses" to the induction of chromatid aberrations by maleic hydrazide (MH) and/or TEM in Vicia faba, Hordeum vulgare, and human periperal blood lymphocytes.. Biologisches Zentralblatt, 112, Gustav Fischer Verlag, Jena, 1993, ISSN:0006-3304, 18 - 27
29. Jovtchev, G., Stergios, M., Rieger, R., Michaelis, A. Effects of the topoisomerase-I inhibitor Camptothecin on the heat shock-triggered adaptive response to maleic hydrazide (MH) in Hordeum vulgare. Biologisches Zentralblatt, 112, 4, Gustav Fischer Verlag, Villengang 2, D-07745 Jena, Germany, 1993, ISSN:0006-3304, 365 - 372
30. Jovtchev, G., Stergios, M., Rieger, R., Michaelis, A. Modulatory effects of novobiocin, actinomycin-D,and caffeine on heat-shock protection against induction of chromatid aberrations by maleic hydrazide in Hordeum vulgare. Biologisches Zentralblatt, 112, 4, Gustav Fischer Verlag, Villengang 2, D-07745 Jena, Germany, 1993, ISSN:0006-3304, 358 - 364
31. Jovtchev, G., Stergois, M. Combined application of "mixed" conditioning procedures simultaneously triggers two independent protective functions against induction of chromatid aberrations by maleic hydrazide in Hordeum vulgare. Comptes rendus de Academie bulgare des Sciences, 52, 3-4, BAS, 1999, ISSN:0861-1459, 103 - 106
32. Varadinova, E., Jovtchev, G., Stergios, M., Doudov, A. Effects of etoposide treatment on the natural level of spontaneous frequency of chromatid aberrations in human somatic cells. Comptes rendus de Academie bulgare des Sciences, 54, 2, BAS, 2001, ISSN:0861-1459, 77 - 80
33. Chankova, S., Jovtchev, G., Gateva, S., Yonova, P., Mehandjiev, A., Shevchenko, V. Protecting effect of newly synthesized urea and thiourea derivatives on different test-systems. Journal of Environmental of Protection and Ecology, 2, 3, BENA, 2001, ISSN:1311-5065, 694 - 703
34. Chankova, S., Kapchina, V., Jovtchev, G., Christova, R. Do unicellular green algae influence toxical and genotoxical action of cadmium in plants.. First European Bioremediation Conference, Chania, Greece, 2001, 178 – 181
35. Gateva, S., Jovtchev, G., Stergios, M., Varadinova, E., Kondakova, E. Complex estimation of the genotoxical potential of pesticides by three cytogenetical test-systems. J. Environmental Protection and Ecology, 2, 3, 2001, 684 – 693
36. Jovtchev, G., Stergios, M. Genotoxic and adaptive effect of cadmium chloride in Hordeum vulgare meristem cells.. Comptes rendus de Academie bulgare des Sciences, 56, 5, BAS, 2003, ISSN:0861-1459, 75 - 80
37. Gateva, S., Jovtchev, G., Stergios, M., Georgieva, V. Cytogenetic studies of combined treatment with cadmium chloride and lontrel in human lymphocytes in vitro. Praemedicus, 1, 5, Marian Nikov, 2003, ISSN: 1314-8079, 14 - 22
38. Jovtchev, G., Yonova, P., Stergios, M., Shevchenko, V.A. Exposure of Hordeum vulgare root tip meristems to 1,1-propylenebis(3-(4-chlorophenyl)) urea does not reduce the frequency of chromatid aberrations induced by UV-C radiation.. Comptes rendus de Academie bulgare des Sciences, 56, 7, BAS, 2003, ISSN:0861-1459, 93 – 98
39. Gateva, S., Azmanov, D., Jovtchev, G., Stergios, M., Arsov, T., Georgieva, V. Apoptosis can be induced by lontrel. Comptes rendus de l’Académie bulgare des Sciences, 57, 9, Издателство на БАН; проф. Марин Дринов, 2004, ISSN:1310-1331, 51 – 56
40. Чанкова, С., Йонова, П.А., Гатева, С.П., Йовчев, Г., Стергиос, М.Л., Механджиев, А.Т., Шевченко, В.А. Эффект 1,1’-hexamethylenbis [3-(3,5-dichloro-4-pyridyl]) urea на дейстие химических мутагеновпри разных типах тестовых систем.. Radiation Biology and Radioecology, 46, 4, НАУКА, 2006, ISSN: 0869-8031, 410 - 414
41. Гатева, С.П., Йонова, П.А., Йовчев, Г., Стергиос, М.Л., Кулекова, С.С. Защитниый эффект вновьсинтезированных соединнений по отношению к повреждающему воздействию УФ-С облучения в человеческих лимфоцитах in vitro. Radiation Biology and Radioecology, 46, 4, NAUKA, 2006, ISSN: 0969-8031, 415 - 419
42. Gateva, S.P., Azmanov, D., Jovtchev, G., Stergios, M., Arsov, T., Georgieva, V. Induction of apoptosis by herbizide devrinol.. Journal of Environmental Protection and Ecology, 7, 2, SCIBULCOM LTD, PO Box 249, 1113 Sofia, Bulgaria, 2006, ISSN:1311-5065, 340 – 346
43. Yonova, P., Gateva, S., Mincheva, N., Jovtchev, G., Stergios, M., Kapchina-Toteva, V. Improvement of tolerance to paraquat in barley (Hordeum vulgare L.) by synthetic thiourea compound: effects on growth and biochemical responses. General and Applied Plant Physiology, 35, 3-4, Published by the Institute of Plant Physiology - Bulgarian Academy of Sciences, 2009, ISSN:1312-8183, 162 - 171
44. Gateva, S., Jovtchev, G., Mitrovska, Z., Stergios, M., Chankova, S. Chlamydomonas reinhardtii modulates and decreases cytotoxic and genotoxic effects of CUSO4. International Journal of Environmental Sciences 5 (3), Integrated Publishing Association, 2014, ISSN:0976 - 4399, DOI:10.6088/ijes.2014050100056, 634 – 648
45. Gateva, S., Jovtchev, G., Stergois, M. Investigation on cytotoxic and genotoxic effects of CUSO4 on Human lymphocytes. Proceedings of the XIX International ECO-Conference 2015, 23-25th september 2015, Novi Sad, Serbia, COBISS, SR-ID 299458055, 2015, ISBN:978-86-83177-4, 249 - 257
46. Jovtchev, G., Stankov, A., Christova, R. Evaluation of cytotoxic and genotoxic potential of soil samples. Proceedings of the XIX International ECO-Conference 2015, 23-25th september 2015, Novi Sad, Serbia, COBISS, SR-ID 299458055, 2015, ISBN:978-86-83177-4, 191 – 199
47. Jovtchev, G., Stankov, A., Gateva, S., Georgieva, A., Dobreva, A., Dimiskovska, B., Mileva, M. Does the essential oil from Rosa alba L. hide cytotoxic and genotoxic potential? Proceedings of the XX International ECO-Conference 2016 – Safe Food, 28-30th September 2016, Novi Sad, Serbia, COBISS, SR-ID 308569095, 2016, ISBN:978-86-83177-51-6, 209-216 Международно неакадемично издателство
48. Gateva, S., Jovtchev, G., Stankov, A., Mileva, M. Geraniol - A component of Rosa alba L. essential oil, possess anti-genotoxic activity against MNNG- induced chromosome aberrations in higher plants and cultured human lymphocytes. Nat Prod Chem Res, 5, 3, 2017, ISSN:2329-6836, DOI:10.4172/2329-6836-C1-014, 70-70 Международно неакадемично издателство
49. Jovtchev, G., Gateva, S., Stankov, A., Todorova, N., Kitanova, M., Topashka-Ancheva, M. Roundup - The best protection or the creeping danger? 21st International Eco-Conference, 12th Eco-Conference on Environmental protection of urban and suburban settlements. Proceedings 2017, Ecological Movement of Novi Sad 21000 Novi Sad, Vojvodjanskih brigada 17/I, 2017, ISBN:978-86-83177-52-3, DOI:COBISS.SR-ID 317216519, 203-212 Международно неакадемично издателство
50. Todorova, N., Stankov, A., Rangelov, M., Jovtchev, G. Has Roundup an impact on microbial commiunities of agricultural soils? Животна средина - Заштита - Зборници, COBISS.SR-ID 317216519, 2017, ISBN: 978-86-83177-52-3, 109-114 Международно неакадемично издателство
51. Rangelov, M., Todorova, N., Jovtchev, G. CellRan: new conceptual program for ecosystem analysis and modelling. Животна средина - Заштита - Зборници, COBISS.SR-ID 317216519, 2017, ISBN: 978-86-83177-52-3, 385-389 Международно неакадемично издателство
52. Beltcheva, M., Aleksieva, I., Metcheva, R., Jovtchev, G., Gateva, S., Dimitrov, D. Small Mammalian Species Diversity and Population Structure Driven by Habitat Heterogeneity In Rila Mountain, Bulgaria. Silva Balkanika, приета за печат: 2019, SJR: 0.13 Без ISI IF – с SJR
Book chapter
53. Barow, M., Jovtchev, G. Endopolyploidy in Plants and its Analysis by Flow Cytometry. Flow Cytometry with Plant Cells, Wiley, 2007, ISBN:987-3-527-3148, 453, 349 – 372
54. Yonova, P. A., Gateva, S., Jovtchev, G. Biological Activity of Novel Ureas and Thioureas Containing Bioactive Heterocycles. Chapter 1. Heterocyclic Compounds and Biological Applications., Science Publishing Group., приета за печат: 2016, ISBN: 978-1-940366-76-0 Международно неакадемично издателство

Affiliation

Department

Ecosystem Research, Environmental Risk Assessment and Conservation Biology

Division

Environmental Mutagenesis and Genetic Risk Assessments

Research group

Genetic Monitoring

Хронология

Член от

10 години 45 седмици