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Borislav Georgiev

Borislav Georgiev's picture

Personal information

Contacts

Institute of Biodiversity and Ecosystem Research
Bulgarian Academy of Sciences
23 Acad. Georgi Bonchev Street
1113, Sofia

e-mail: bobogeorgiev5@gmail.com

Curriculum vitae

Date and place of birth: 10.02.1998, Sofia, Bulgaria

Education
2016-2020: BSc in Molecular biology, Faculty of Biology, Sofia University
2020-2022: MSc in Microbiology and microbial control, Faculty of Biology, Sofia University

https://orcid.org/0009-0000-7255-7965
https://www.scopus.com/authid/detail.uri?authorId=57223199659
https://www.researchgate.net/profile/Borislav-Georgiev-2

Publications

1. Kancheva D., Nikolova M., Georgiev V., Georgiev B., Yankova-Tsvetkova E., Aneva I. (2026) Species-Specific Metabolite Profiles and Biological Activities of Bulgarian Thymus Species from Section Hyphodromi. Plants, 15(6), 927. doi: 10.3390/plants15060927
https://doi.org/10.3390/plants15060927

2. Mateev E., Georgiev B., Pavlova E., Irfan A., Muhammed M.T., Momekov G., Georgieva M., Kondeva-Burdina M. (2025) Integrated experimental and computational study of novel pyrrole derivatives: Microwave-assisted synthesis, enzyme inhibition, antioxidant properties, and neurotoxicity evaluation. Letters in Drug Design & Delivery, 22(10), 100205. doi: 10.1016/j.lddd.2025.100205
https://doi.org/10.1016/j.lddd.2025.100205

3. Mateev E., Chtita S., Pavlova E., Irfan A., Tzankova D., Sharma S., Georgiev B., Mateeva A., Momekov G., Georgieva M., Zlatkov A., Kondeva-Burdina M. (2025) Design, Synthesis, and Evaluation of Pyrrole-Based Selective MAO-B Inhibitors with Additional AChE Inhibitory and Neuroprotective Properties Identified via Virtual Screening. Pharmaceuticals, 18(11), 1677. doi: 10.3990/ph18111677
https://doi.org/10.3390/ph18111677

4. Nikolova M., Lyubenova A., Yankova-Tsvetkova E., Georgiev B., Gavrilov G., Gavrilova A. (2025) Satureja kitaibelii Essential Oil and Extracts: Bioactive Compounds and Pesticide Properties. Agronomy, 15(2), 357. doi: 10.3390/agronomy15020357
https://doi.org/10.3390/agronomy15020357

5. Georgiev B., Sidjimova B., Berkov S. (2024) Phytochemical and Cytotoxic Aspects of Amaryllidaceae Alkaloids in Galanthus Species: A Review. Plants, 13(24), 3577. doi: 10.3390/plants13243577
https://www.mdpi.com/2223-7747/13/24/3577

6. Atanasova M., Stavrakov G., Philipova I., Georgiev B., Bastida J., Doytchinova I., Berkov S. (2024) AChE inhibitory activity of N-substituted natural galanthamine derivatives. Bioorganic & Medicinal Chemistry Letters, 112, 129937. doi: 10.1016/j.bmcl.2024.129937
https://www.sciencedirect.com/science/article/abs/pii/S0960894X24003391

7. Sidjimova B., Georgiev B., Nikolova M., Yankova-Tsvetkova E., Denev R., Berkov S. (2024) Biological Activity of Different Alkaloid Chemotypes of Galanthus elwesii and Galanthus nivalis. Comptes rendus de l’Acad´emie bulgare des Sciences, 77(5), 657-668. doi: 10.7546/CRABS.2024.05.03
https://www.proceedings.bas.bg/index.php/cr/article/view/534

8. Nikolova M., Lyubenova A., Yankova-Tsvetkova E., Georgiev B., Berkov S., Aneva I., Trendafilova A. (2023) Artemisia santonicum L. and Artemisia lerchiana Web. Essential Oils and Exudates as Sources of Compounds with Pesticidal Action. Plants, 12(19), 3491. doi: 10.3390/plants12193491
https://www.mdpi.com/2223-7747/12/19/3491

9. Angelova T., Georgiev B., Pencheva T., Pajeva I., Rangelov M., Todorova N., ZhelevaDimitrova D., Kalcheva-Yovkova E., Valkova I., Vassilev N., Mihaylova R., Stefanova D., Petrov B., Voynikov Y., Tzankova V. (2023) Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole- and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer’s Disease. Pharmaceuticals, 16(9), 1194. doi: 10.3390/ph16091194
https://www.mdpi.com/1424-8247/16/9/1194

10. Atanasova M., Dimitrov I., Ivanov S., Georgiev B., Berkov S., Zheleva-Dimitrova D., & Doytchinova I. (2022). Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors. Molecules, 27(10), 3139. doi: 10.3390/molecules27103139
https://www.mdpi.com/1420-3049/27/10/3139

11. Georgiev B., Nikolova M., Aneva I., Dzhurmanski A., Sidjimova B., & Berkov S. (2022). Plant products with acetylcholinesterase inhibitory activity for insect control. BioRisk, 17: 309-315. doi: 10.3897/biorisk.17.77052
https://biorisk.pensoft.net/article/77052/download/pdf/

12. Berkov S., Atanasova M., Georgiev B., Bastida J., & Doytchinova I. (2021). The Amaryllidaceae alkaloids: an untapped source of acetylcholinesterase inhibitors. Phytochemistry Reviews. doi: 10.1007/s11101-021-09790-0
https://link.springer.com/article/10.1007/s11101-021-09790-0

13. Stavrakov G., Philipova I., Lukarski A., Atanasova M., Georgiev B., Atanasova T., Konstantinov S., Doytchinova I., Muñoz-Torrero D. (2021). Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening. Molecules, 26(7), 2058.
doi: 10.3390/molecules26072058
https://www.mdpi.com/1420-3049/26/7/2058

Participation in projects:

1. ПВУ-67, 16.12.2024, BG-RRP-2.017-0021-C01. Method for the extraction of galanthamine from an innovative raw material. Project coordinator: prof. Strahil Berkov, PhD, IBER-BAS.

2. КП-06 ПМ83/1, 2024. Drug design and synthesis of new multi-target molecules for the treatment of Parkinson’s disease. Project coordinator: assist. prof. Emilio Mateev, PhD, Medical University-Sofia.

3. КП-06 ПН76/24, 05.12.2023. Galanthamine biosynthesis during soilless vertical cultivation of Hippeastrum papilio (Ravenna) Van Scheepen. Project coordinator: prof. Strahil Berkov, PhD, IBER-BAS.

4. КП-06-Н76/5, 05.12.2023. Biotechnological approaches for the targeted accumulation of secondary metabolites in the medicinal plant Arnica montana L. and research on the biosynthetic pathways for sesquiterpenoid lactones. Project coordinator: assist. prof. Maria Petrova, PhD, IPPG-BAS.

5. КП-06-Н63/11, 14.12.2022. Neuropharmacological studies of newly synthesized sulfanyl hydrazones and melatonin derivatives with cholinesterase inhibitory activity in models of Alzheimer's disease and melatonin deficiency. Project coordinator: assoc. prof. Violina Stoyanova, PhD, Medical University-Sofia.

Affiliation

Department
Plant and Fungal Diversity and Resources
Division
Applied Botany
Research group
Chemoecology and natural products RG

History

Member for
8 years 13 weeks


by Dr. Radut.