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Teodora Todorova

Teodora Todorova's picture

Personal information

Contacts

Institute of Biodiversity and Ecosystem Research
2 Yurii Gagarin Street
1113 Sofia
Bulgaria
e-mail: tedi_todorova@yahoo.com; teodora.todorova@iber.bas.bg
Teodora Todorova on ResearchGate
https://orcid.org/0000-0003-1075-4482
Scopus Author ID: 55811219600
Web of Science ResearcherID: H-5169-2015
Loop profile: 278013

Curriculum vitae

Date and place of birth: 28th December 1986, Montana, Bulgaria

Education:
2009- BSc in Molecular Biology, Sofia University "St.Kliment Ohridski"
2011- MSc in Genetics, Sofia University "St.Kliment Ohridski"
2015 - PhD in Genetics, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences

Project participation
2009 - 2011 - Participant “Mutagenic effect of low temperatures on nuclear DNA of eukaryotic cells”, funded by National Science Fund of Sofia University “St. Kliment Ohridski”, Project leader: Dr. Margarita Pesheva, Faculty of Biology, Sofia University “St. Kliment Ohridski”, Bulgaria

2012 - 2014 - Participant „Evaluation of DNA protective potential of biologically active natural compounds against DNA damaging factors", funded by National Science Fund,(DNTS01/1/Slovakia) Project leader: prof. Stephka Chankova, Institute of Biodiversity and Ecosystem Research - BAS, Bulgaria

2016 - 2019 - Coordinator “Strategies for overcoming the genetic risk of anthropogenic pollution with organophosphorus pesticides”, Bilateral agreement between Bulgarian Academy of Sciences and National Research Center, Egypt

2016 - Coordinator “DNA protective potential in vitro cultivated Clinopodium vulgare L. plant extracts”, funded by Ministry of Education and Science, Bulgaria

2018 – 2020 – Participant “Saccharomyces cerevisiae quiescence – smart model for toxicological and stress response research”, funded by National Science Fund - Ministry of Education and Science; Project coordinator: Assoc. Prof. Ventsislava Petrova, PhD.

2018 - 2020 Participant "Biocidal activity of extracts from Bulgarian plants - screening and potato crop protection"

2019 - 2022 Coordinator “Preparation and characterization of eco-friendly green and nanopesticides for spider mites and aphids control” Bilateral agreement between Bulgarian Academy of Sciences and National Research Center, Egypt

2019 - 2023 Coordinator to work task "Invasive plant species as a source of valuable biologically active substances", National Science Program "Environmental Protection and Reduction of Risks of Adverse Events and Natural Disasters"

2020 - 2023 Participant "Crystal-chemical and structural characteristics of modified natural clinopltilolite and correlation between its sorption properties, ion exchange capacity for heavy metals and biological response in vivo and in vitro"

2022 - 2024 Coordinator "Nano-based green adsorbents from agriculture wastes for removal of pesticide residues and heavy metals", Bilateral agreement between Bulgarian Academy of Sciences and National Research Center, Egypt

Membership:
The Genetics Society of America – since 11/2015 – 12/2017

National Postdoctoral Association – since 11/2015 – 12/2016

Union of Scientists in Bulgaria – Section Biology – since 09/2013 - present

Participation in national/international meetings

1.Todorova T., 2008, “Manganese and Parkinson’s disease”, 3rd workshop on biological activity of metals and metal compounds, 19-20 November, 2008, Bulgarian Academy of Sciences, Sofia, Bulgaria.

2.Georgieva M., Todorova T., 2008, “Chromium and cancer”, 3rd workshop on biological activity of metals and metal compounds, 19-20 November, 2008, Bulgarian Academy of Sciences, Sofia, Bulgaria.

3.Todorova T., 2008 “Abelson murine leukemia virus”, Seminar on virus-induced cancerogenesis, Bulgarian Academy of Sciences, Sofia, Bulgaria.

4.Todorova T., 2008 “Simian Gammaherpesviruses”, Seminar on virus-induced cancerogenesis, Bulgarian Academy of Sciences, Sofia, Bulgaria.

5.Todorova T., Popova T., Alexandrova R., Georgieva M., Farràs. P, Viñas, C., 2009, “Newly synthesized metallacarboranes: Investigations on antimicrobial activity and effect on viability of cultured nontumor cells”, International Medical Students’ Research Congress 2009, 8-10 May, 2009, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

6.Georgieva M., Popova T., Alexandrova R., Todorova T., Grozav M., Crisan M., Simu G., Grad M., 2009, “Investigations on antimicrobial activity in vitro of some sodium salts of 4,4’- diaminostilben-2,2’- disulfonic acid and compounds of para- substituted benzoic acids with morpholine”, International Medical Students’ Research Congress 2009, 8-10 May, 2009, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

7.Todorova T., M. Georgieva, 2009, “Zinc fingers- role in restriction enzymes and gene therapy”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

8.Todorova T., M. Georgieva, 2009, “Silver and its usage in wound treatment”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

9.R. Alexandrova, M. Georgieva, T. Todorova, D. Culita, G. Marinescu, L. Patron, 2009, “Let us remember zinc”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

10.Todorova T., 2010, “ Yeasts as a model system”, Workshop on experimental models and methods in biomedical researches, 16-17 March, 2010, Bulgarian Academy of Sciences, Sofia, Bulgaria

11.Todorova T., R. Stamenova , 2010, Cryopreservation causes replication fork stalling and activates the S- phase checkpoints in yeast Saccharomyces cerevisiae” 3rd Pan Arab Human Genetics Conference, Dubai, UAE

12.Todorova T., R. Stamenova, M. Pesheva, 2010, “ Microsatellite DNA- indicator for mutations caused by low temperatures”, Младежка научна конференция „ Климентови дни”, Биологически факултет, София, България

13.Todorova T., M. Pesheva, 2011, “Mutagenic effect of low temperatures on nuclear DNA in yeast Saccharomyces cerevisiae”, Bulgarian Academy of Sciences, Sofia, Bulgaria

14.Todorova T., M. Pesheva. 2012. Mutagenic effect of freezing on nuclear DNA of Saccharomyces cerevisiae. Seminar of Ecology, April, 2012

15.Todorova T., M. Pesheva, S. Chankova. 2012. Antioxidant and anticarcinogenic effect of Papaver rhoeas L. extract on test- system Saccharomyces cerevisiae. 4th Congress of Ecologists of the Republic of Macedonia. Октомври 2012

16.Mahmud A., T. Todorova, S. Chankova. 2012. Biological effect of polluted soil samples on green alga Chlamydomonas reinhardtii. 4th Congress of Ecologists of the Republic of Macedonia. Октомври 2012

17.Todorova T., M. Pesheva, S. Chankova. 2013. Antimutagenic effect of Papaver rhoeas L. extract on test- system Saccharomyces cerevisiae - „Seminar of Ecology – 2013“, 25–26 April, Sofia

18. A. Mahmud, T. Todorova, Z. Mitrovska, S. Chankova. 2013. Impact of polluted soils on DNA and HSP70B of Chlamydomonas reinhardtii- „Seminar of Ecology – 2013“, 25–26 April, Sofia

19.Todorova T., Daniela Miteva, Ventzislav Bardarov, Krum Bardarov, Atanas Atanassov, Stephka Chankova (2014) Protective activity of different extracts of Clinopodium vulgare L., Seminar of Ecology with international participation - 2014, 24-25 April 2014, Sofia, Bulgaria.

20.Bardarov V., S. Konstantinov, K. Bardarov, T. Todorova, St. Chankova, M. Shishinjova and A. Atanasov (2014) Medical plants a case study on Clinopodium vulgare L., The 8th Meeting with International Participation TOGETHER IN CANCER CONTROL:IMMUNOLOGY, VIRISES, NATURAL PRODUCTS, 24-25 October 2014, Pleven, Bulgaria.

21.Todorova, T., Miteva, D., Pesheva, M., Chankova, S. (2015) Protective activity of Clinopodium vulgare L. leaves on Saccharomyces cerevisiae nuclear DNA, 2nd National Food Conference with international participation, 20-21 March, 2015, Sofia, Bulgaria.

22.Todorova, T., Miteva, D., Pesheva, M., Chankova, S. (2015) DNA double strand breaks repair capacity in yeast Saccharomyces cerevisiae after zeocin treatment, Seminar of Ecology with international participation - 2015, 23-24 April 2015, Sofia, Bulgaria.

23. Todorova, T., Miteva, D., Radovanova, N., Ivanova, I., Chankova, S. (2016) Role of genotype and experimental design for Saccharomyces cerevisiae DNA protection against zeocin-induced double-strand breaks by Clinopodium vulgare, Seminar of Ecology with international participation - 2016, 21-22 April 2016, Sofia, Bulgaria.

24. Radovanova, N., Ivanova, I., Todorova, T., Chankova, S. (2016) Does combined treatment with Clinopodium vulgare extract and zeocin protect nuclear DNA from zeocin-induced damages?, Seminar of Ecology with international participation - 2016, 21-22 April 2016, Sofia, Bulgaria.

25. Parvanova P., Todorova T., Miteva D., Mitrovska Zh., Chankova S. DNA SUSCEPTIBILITY OF CHLAMYDOMONAS REINHARDTII AND SACCHAROMYCES CEREVISIAE TO NURELLE D Seminar of Ecology - 2017 with international participation, 27-28 April, 2017, Sofia, Bulgaria.

26. Todorova, T., Parvanova, P., Mossa, AT., Kostadinov, K., Dimitrov, M., Iliev, I., Mitrovska, Zh., Angelova T., Chankova, S. (2018) Nurelle D bioactivity depending on the test system, 11th Annual Seminar of Ecology – 2018 with international participation, 26 – 27 April 2018, Sofia, Bulgaria.

27. Todorova T, Parvanova P, Dimitrova M, Mitrovska Zh, Chankova S. (2019) Optimization of CFGE for Saccharomyces cerevisiae strain with a wild type cell wall structure, International Seminar of Ecology – 2019”, 18 - 19 April 2019, Sofia, Bulgaria.

28. Todorova T, Chankova S. (2019)Saccharomyces cerevisiae - a suitable model for environmental studies, The 1st NRC-Grenoble INP International Conference on Science and Sustainable Development,16 - 18 September 2019, Cairo, Egypt - Keynote speaker

29. Parvanova P., Dimitrova M., Yovkova M., Todorova T., Miteva D., Mitrovska Zh.,Chankova S. (2019) Comparative analysis of the biological activity of natural and chemical compounds on a battery of test systems, The 1st NRC-Grenoble INP International Conference on Science and Sustainable Development,16 - 18 September 2019, Cairo, Egypt

30. Мария Димитрова, Теодора Тодорова, Мария Йовкова, Петя Първанова, Красимир Бояджиев, Стефка Чанкова. Сравнителен анализ на антиоксидантната активност на растителни екстракти с различен произход , Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад

31.Теодора Тодорова, Петя Първанова, Мария Димитрова, Мария Йовкова, Стефка Чанкова (2019) ДНК “Topology“ тест – подходящ метод за определяне на антиоксидантна и ДНК защитна активност на природни продукти с растителен произход , Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад - получена награда за най-добър доклад на млад учен

32. Стефка Чанкова-Петрова, Т. Тодорова, М. Димитрова, П. Първанова, Д. Митева, Е. Димова, А. Айдън, Ж. Митровска. М. Йовкова (2019) Мутагенеза от околната среда - проблем на съвремието ни, Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад

33. Тодорова, Т., Първанова, П., Димитрова, М., Йонкова, И., Кръстева, И., Шкондров, А., Митровска, Ж., Кожухарова, Е., Чанкова, С.. Дали екстракт от плодове на Amorpha fruticosa проявява генотоксичен и мутагенен ефект върху Saccharomyces cerevisiae или не? 7th Congress of pharmacy with international participation; Borovets, Bulgaria; 21.11.2019 - 24.11.2019 - постер

34. Yovkova, M., Parvanova, P., Dimitrova, M., Todorova, T., Chankova, S. Natural products with potential aphicidal effect, XIV Workshop "Biological activity of metals, synthetic and natural products" Sofia, Bulgaria; 02.12.2019 - 04.12.2019 (Доклад)

35.Zidarova, E., Parvanova, P., Dimitrova, M., Dronchev, G, Todorova, T., Dimitrov, M, Yovkova, M., Chankova, S.Different response of two model systems to the action of essential oils with plants origin, XIV Workshop "Biological activity of metals, synthetic and natural products" Sofia, Bulgaria; 02.12.2019 - 04.12.2019 (Доклад)

36.Boyadzhiev, K., Dimitrov, M, Blazhev, G, Todorova, T., Chankova, S..
Genotoxic effect of bee venom on Saccharomyces cerevisiae; XIV Workshop "Biological activity of metals, synthetic and natural products" Sofia, Bulgaria; 02.12.2019 - 04.12.2019 (Доклад)

37.Parvanova, P., Todorova, T., Çavuş, H., Yovkova, M., Dimitrova, M., Boyadzhiev, K., Dimitrov, M, Chankova, S., Genotoxic and mutagenic potential of chlorpyrifos on Sacchromyces cerevisiae and Chlamydomonas reinhardtii, XIV Workshop "Biological activity of metals, synthetic and natural products" Sofia, Bulgaria; 02.12.2019 - 04.12.2019 (Доклад)

38. Todorova T., Parvanova P., Çavuş H., Yovkova M., Dimitrova M., Mossa AT, Boyadzhiev K., Dimitrov M., Chankova S., Set of tests for chlorpyrifos toxicity screening, "International Seminar of Ecology – 2020”, 23 - 24 April 2020, Online, Sofia, Bulgaria.

39. Miteva D., Todorova T., Chankova S., How Chlorella Species respond to UV-B induced stress, "International Seminar of Ecology – 2020”, 23 - 24 April 2020, Online, Sofia, Bulgaria.

40. Todorova T., Ivanova I., Yovkova M., Dimitrova M., Parvanova P., Dimitrov M., Chankova S. DNA repair capacity of Saccharomyces cerevisiae after single and combined treatment with zeocin and different concentrations Clinopodium vulgare L. Extract, the Ninth International Conference on Radiation in Various Fields of Research, 14 - 10 June, 2021, Herceg Novi, Montenegro

41. Dimitrova, M., Parvanova, P., Todorova, T., Dronchev, G.,
Nikolova, M., Berkov S. and Chankova S., On the mode of action of Origanum vulgare spp. hirtum methanolic extract and essential oil on Chlamydomonas reinhardtii, INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

42. Dimitrova, M., Parvanova, P., Todorova, T., Nikolova, M., Berkov S. and Chankova S.,Polar and nonpolar fraction from Origanum vulgare spp. hirtum methanolic extract - differences in their bioactivity on Chlamydomonas reinhardtii test system., INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

43. Parvanova, P., Yovkova, M., Dimitrova, M., Todorova, T., Boyadzhiev, K., Nikolova, M., Berkov S. and Chankova S.,On the bioactivity of Origanum vulgare essential oil in Myzus persicae and potato plants., INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

44. Boyadzhiev, K., Todorova, T., Shkondrov, A., Parvanova, P., Dimitrova, M., Ionkova, I., Krasteva, I., Kozuharova E. and Chankova S., Screening of Amorpha fruticosa and Ailanthus altissima extracts for genotoxicity, mutagenicity and carcinogenicity.,INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

45. Marinovska, P., Todorova, T., Boyadzhiev, K., Pisareva, E., Tomova, A., Parvanova, P., Dimitrova, M., Petrova V. and Chankova S., Cellular susceptibility and oxidative stress response to Menadione of logarithmic, quiescent and nonquiescent Saccharomyces cerevisiae cell populations.INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

46. Marinovska, P., Todorova, T., Tomova, A., Pisareva, E., Boyadzhiev, K., Dimitrov, M., Parvanova, P., Dimitrova, M., Chankova S. and Petrova V., Quiescent yeast cells for assessing Zeocin toxicity., INTERNATIONAL SEMINAR OF ECOLOGY- 2021 Current Trends of Ecology, September 29th - 30th, 2021, Online, Sofia, Bulgaria.

47. Todorova, T., Miteva, D., Chankova, S., DSBS as a triggering event for the formation of an adaptive response in Saccharomyces cerevisiae., V International Conference MODERN PROBLEMS OF GENETICS, RADIOBIOLOGY, RADIOECOLOGY AND EVOLUTION dedicated to N. W. Timofeeff-Ressovsky and his scientific school, October 5th - 9th, 2021, Yerevan, Armenia.

48. Boyadzhiev, K., Todorova, T., Dimitrov, M., Dimitrova, M., Parvanova, P., Chankova, S. BIOLOGICAL ACTIVITY OF BEE VENOM ON A MODEL ORGANISM SACCHAROMYCES CEREVISIAE, ANKARA INTERNATIONAL CONGRESS ON SCIENTIFIC RESEARCH-VI, April 1-3, 2022, Ankara - TURKEY.

49. Zidarova, E., Todorova, T., Parvanova, P., Dimitrova, M., Boyadzhiev, K., Dimitrov, M., Chankova, S.COMPARATIVE ASSESSMENT OF GENOTOXIC AND DNA DAMAGING POTENTIAL OF ESSENTIAL OILS ON CHLAMYDOMONAS REINHARDTII AND SACCHAROMYCES CEREVISIAE, ANKARA INTERNATIONAL CONGRESS ON SCIENTIFIC RESEARCH-VI, April 1-3, 2022, Ankara - TURKEY.

50. Parvanova, P., Todorova, T., Dimitrova, M., Dimitrov, M., Boyadzhiev, K., Sidjimova, B., Nikolova, M., Berkov, S., Chankova, S.ON THE MODE OF ACTION OF NARCISSUS CV HAWERA TOTAL LEAVES EXTRACT ON CHLAMYDOMONAS REINHARDTII, ANKARA INTERNATIONAL CONGRESS ON SCIENTIFIC RESEARCH-VI, April 1-3, 2022, Ankara - TURKEY.

51. Todorova, T., Alexieva, I., Ostoich, P., Dimitrova, M., Boyadzhiev, K., Beltcheva, M. Lead and cadmium induce different oxidative stress profiles in the liver and kidneys of subchronically exposed mice, International Scientific Conference - GREEN DEVELOPMENT, GEEEN INFRASTRUCTURE, GREEN TECHNOLOGY, 06-08.05.2022, Skopje, North Macedonia

52. Todorova, T., Parvanova, P., Dimitrova, M., Zahariev, K., Boyadzhiev, K., Dimitrov, M., Chankova, S. Genotype differences towards lead chloride toxicity, International Seminar of Ecology - 2022 Actual problems in Ecology, 29 - 30.09.2022, Sofia, Bulgaria

53. Chankova, S., Yurina, N., Sharapova, L., Todorova, T., Parvanova, P. Does overproduction of chaperone proteins favor the repair of DNA injuries induced by oxidative stress?International Seminar of Ecology - 2022 Actual problems in Ecology, 29 - 30.09.2022, Sofia, Bulgaria (plenary)

54. Chankova, S., Parvanova, P., Todorova, T., Yurina, N.Mechanisms involved in the formation of genotype resistance - the contribution of DSB repair, chaperone and antioxidant systems, Armenian meeting-2023 "Climate change: adaptation", March 27-28, 2023, Yerevan, Armenia (oral presentation)

55. Todorova, T., Parvanova, P., Chankova, S. The Saccharomyces cerevisiae response to various stressors strongly depends on the genotype characteristics, Armenian meeting-2023 "Climate change: adaptation", March 27-28, 2023, Yerevan, Armenia (oral presentation)

56. Todorova, T., Parvanova, P., Boyadzhiev, K., Chankova, S., DNA damaging capacity of PbCl2 and the role of mismatch repair system, International Seminar of Ecology – 2023 "Cutting Edge Research of Ecology", September 28-29, 2023, Sofia, Bulgaria (oral presentation)

57. Todorova, T., Boyadzhiev, K., Parvanova, P., Chankova, S., DNA damaging/protective capacity of Amorpha fruticosa and Ailanthus altissima extracts depend on the type and chemical composition, International Seminar of Ecology – 2023 "Cutting Edge Research of Ecology", September 28-29, 2023, Sofia, Bulgaria (oral presentation)

58. Todorova, T., Parvanova, P., Boyadzhiev, K., Dimitrov, M., Chankova, S.Differential response of Chlamydomonas reinhardtii and Saccharomyces cerevisiae to cadmium chloride short-term treatment, International Seminar of Ecology – 2023 "Cutting Edge Research of Ecology", September 28-29, 2023, Sofia, Bulgaria (oral presentation)

59. Parvanova, P., Todorova, T., Boyadzhiev, K., Chankova, S. Pisum sativum L. stress response to single and combined treatment with heavy metals, International Seminar of Ecology – 2023 "Cutting Edge Research of Ecology", September 28-29, 2023, Sofia, Bulgaria (oral presentation)

60. Boyadzhiev, K., Todorova, T., Dimitrov, M., Parvanova, P., Chankova, S. Genotype-related differences in two Saccharomyces cerevisiae strains towards heavy metal treatment, Youth scientific conference "60 years" Department of "General and Industrial Microbiology", November, 17th, 2023, Sofia, Bulgaria (poster presentation)

Teaching
2015 - 10 hours - Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2018 - 30 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2019 - 30 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2020 - 30 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2021 - 150 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2022 - 60 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2022 - 30 hours - Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2023 - 45 hours - Bacterial Genetics, Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria

Supervising master students

1. Iviyana Ivanova – 2016, M. Sc. in Microbiology, Thesis title: “DNA protective potential of Clinopodium vulgare L. extract and role of experimental design”

2. Kostadin Kostadinov – 2017, M. Sc. in Gene and Cellular engineering, Thesis title: “Study of the promutagenic and procarcinogenic potential of the pesticide Nurelle D”

3. Georgi Blazhev - 2020, M.Sc. in Gene and Cellular engineering, Thesis title: "The role of genotype and experimental design for the induction of adaptive response to Zeocin in yeast Saccharomyces cerevisiae"

4. Elena Zidarova - 2021 M.Sc. in Gene and Cellular engineering, Thesis title: "Bioactivity of essential oils on two model systems - Chlamydomonas reinhardtii and Saccharomyces cerevisiae"

5. Krassimir Boyadzhiev - 2021 M.Sc. in Genetics and Genomics, Thesis title: Evaluation of the bioactivity of bee venom by in vivo method on a test system Saccharomyces cerevisiae

Research interests

- Saccharomyces cerevisiae
- antimutagenesis, anticarcinogenesis
- mechanisms of induction and repair of DSBs
- Ty1 retrotransposition
- Adaptive response
- Natural products
- Microsatellite DNA
- Genome stability
- Protein remodeling
- Oxidative stress

Publications

1. Todorova, T., Pesheva, M., Stamenova, R., Dimitrov, M., Venkov, P, 2012, Mutagenic effect of freezing on nuclear DNA of Saccharomyces cerevisiae. Yeast, 29, 191–199. doi: 10.1002/yea.2901. (IF=1.955;Q1)

2. Chankova, S., Todorova, T., Parvanova, P., Miteva, D., Mitrovska, Z., Angelova, O., Imreova, P., Mucaji, P., 2013, Kaempferol and jatropham: are they protective or detrimental for Chlamydomonas reinhardtii? Comptes rendus de I`Académie bulgare des Sciences, 66(8), 1121- 1128. (IF=0.211; Q2)

3. Todorova, T., Miteva, D., Chankova, S., 2015, DNA damaging effect of zeocin and methyl methanesulfonate in Saccharomyces cerevisiae measured by CFGE, Comptes rendus de I`Académie bulgare des Sciences, 68(1), 71-78. (IF=0.198; Q2)

4. Todorova, T., Pesheva, M., Gregan, F., Chankova, S., 2015, Antioxidant, antimutagenic and anticarcinogenic effects of Papaver rhoeas L. extract on Saccharomyces cerevisiae, Journal of Medicinal Food, 18(4): 460-467. doi:10.1089/jmf.2014.0050 (IF=1.622; Q2)

5. Bardarov, K.,Todorova, T., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S.(2016) Preliminary screening for study of the chemical composition of Clinopodium vulgare L. water extract, Comptes rendus de I`Académie bulgare des Sciences, 69(6), 717-724 (IF=0.233; Q2)

6. Todorova, T., Bardarov, K., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S.(2016) DNA protective activities of Clinopodium vulgare L. extracts, Comptes rendus de I`Académie bulgare des Sciences, 69(8), 1019-1024 (IF=0.233; Q2)

7. Todorova, A., Pesheva, M., Iliev, I., Bardarov, K., Todorova, T. Antimutagenic, Antirecombinogenic, and Antitumor Effect of Amygdalin in a Yeast Cell–Based Test and Mammalian Cell Lines, Journal of Medicinal Food, 2017, 20(4): 360-366. doi:10.1089/jmf.2016.0108 (IF=1.844; Q2)

8. Todorova, T, Miteva, D., Chankova, S. DNA susceptibility of Saccharomyces cerevisiae to Zeocin depends on the growth phase, International Microbiology, 2019, 22, 419–428, (IF=1.256; Q3) https://doi.org/10.1007/s10123-019-00065-5

9. Miteva, D, Todorova, T, Chankova, S. How Chlorella species isolated from contrasting habitats respond to UV-B induced stress?. Ecologia Balkanica, Special edition 3, 19 - 30, 2020, SJR (Scopus):0.13, Q4 (Scopus)

10. Todorova, T, Parvanova, P, Çavuş, H, Yovkova, M, Dimitrova, M, Mohafrash, S, Mossa, AT, Boyadzhiev, K, Dimitrov, M., Chankova, S. Set of tests for chlorpyrifos toxicity screening. Ecologia Balkanica, 2020, Special edition 3, 227-238, SJR (Scopus):0.13, Q4 (Scopus)

11. Dimitrov, M., Iliev, I., Bardarov, K., Georgieva, D., & Todorova, T. (2021). Phytochemical characterization and biological activity of apricot kernels’ extract in yeast-cell based tests and hepatocellular and colorectal carcinoma cell lines. Journal of Ethnopharmacology, 114333. (IF=4.360 Q1)

12.Dimitrova, M, Miteva, D, Todorova, T, Parvanova, P, Yovkova, M, Dimitrov, M., Chankova, S. DNA-REPAIR DEFICIENT STRAINS CHLAMYDOMONAS REINHARDTII AS GOOD TOOLS FOR ENVIRONMENTAL TOXICOLOGY. Comptes rendus de l’Académie bulgare des Sciences, 2022, 75, 2, 223-229, JCR-IF (Web of Science):0.378; Q2 (Scopus)

13. Dimitrova, M, Parvanova PN, Todorova TI, Dronchev GD, Nikolova MT, Berkov SH, Chankova SG (2021) On the mode of action of Origanum vulgare spp. hirtum methanolic extract and essential oil on Chlamydomonas reinhardtii. In: Chankova S, Peneva V, Metcheva R, Beltcheva M, Vassilev K, Radeva G, Danova K (Eds) Current trends of ecology. BioRisk 17: 179-190. https://doi.org/10.3897/biorisk.17.77313 (SJR (Scopus):0.24 Q2)

14. Todorova T, Boyadzhiev K, Shkondrov A, Parvanova P, Dimitrova M, Ionkova I, Krasteva I, Kozuharova E, Chankova S (2022) Screening of Amorpha fruticosa and Ailanthus altissima extracts for genotoxicity/antigenotoxicity, mutagenicity/antimutagenicity and carcinogenicity/anticarcinogenicity. In: Chankova S, Peneva V, Metcheva R, Beltcheva M, Vassilev K, Radeva G, Danova K (Eds) Current trends of ecology. BioRisk 17: 201-212. https://doi.org/10.3897/biorisk.17.77327 (SJR (Scopus):0.24 Q2)

15. Marinovska P, Todorova T, Tomova A, Pisareva E, Boyadzhiev K, Dimitrov M, Parvanova P, Dimitrova M, Chankova S, Petrova V (2022) Saccharomyces cerevisiae yeast cells as a test system for assessing Zeocin toxicity. In: Chankova S, Peneva V, Metcheva R, Beltcheva M, Vassilev K, Radeva G, Danova K (Eds) Current trends of ecology. BioRisk 17: 105-116. https://doi.org/10.3897/biorisk.17.77227, (SJR (Scopus):0.24 Q2)

16. Dimitrova M, Parvanova PN, Todorova TI, Nikolova MT, Berkov SH, Chankova SG (2022) Polar and non-polar fraction from Origanum vulgare spp. hirtum methanolic extract – differences in their bioactivity on Chlamydomonas reinhardtii test system. In: Chankova S, Peneva V, Metcheva R, Beltcheva M, Vassilev K, Radeva G, Danova K (Eds) Current trends of ecology. BioRisk 17: 191-200. https://doi.org/10.3897/biorisk.17.78169 (SJR (Scopus):0.24 Q2)

17. Marinovska PG, Todorova TI, Boyadzhiev KP, Pisareva EI, Tomova AA, Parvanova PN, Dimitrova M, Chankova SG, Petrova VY (2022) Cellular susceptibility and oxidative stress response to menadione of logarithmic, quiescent, and nonquiescent Saccharomyces cerevisiae cell populations. In: Chankova S, Peneva V, Metcheva R, Beltcheva M, Vassilev K, Radeva G, Danova K (Eds) Current trends of ecology. BioRisk 17: 127-138. https://doi.org/10.3897/biorisk.17.77320 (SJR (Scopus):0.24 Q2)

18. Todorova, A., Todorova, T.. Apricot kernels’ extract and amygdalin alter bleomycin-induced Ty1 retrotransposition, mitotic gene conversion in the trp-5 locus and reverse point mutations in ilv1-92 allele in Saccharomyces cerevisiae. Archives of Microbiology, 204, 2022, DOI:10.1007/s00203-022-03155-7, SJR (Scopus Q2):0.59, JCR-IF (Web of Science):2.667

19. Ignatov, I., Neshev, N., Popova, T., Kiselova-Kaneva, Y., Drossinakis, C., Bankova, R., Toshkova, R., Gluhchev, G., Valcheva, N., Angelcheva, M., Dinkov, G., Angushev, I., Todorova, T., Balabanski, V., Baiti, S., Huether, F., Ignatov, A.. Theoretical Analysis of Hydrogen Bonds, Energy Distribution and Information in a 1 % Rosa damascena Mill Oil Solution. PLANT SCIENCE TODAY, 9, 3, HORIZON e-Publishing Group, 2022, DOI:https://doi.org/10.14719/pst.1645, 760-765. SJR (Scopus Q3):0.21

20. Kozuharova, E., Pasdaran, A., Al Tawaha, A.R., Todorova, T., Naychov, Z., Ionkova, I.. Assessment of the Potential of the Invasive Arboreal Plant Ailanthus altissima (Simaroubaceae) as an Economically Prospective Source of Natural Pesticides. Diversity, 14, 8, MDPI, 2022, DOI:https://doi.org/10.3390/d14080680, 680. SJR (Scopus Q1):0.67, JCR-IF (Web of Science):3.029

21. Huether, F., Ignatov, I., Kiselova-Kaneva, Y., Popova, T. P., Bankova, R., Neshev, N., Gluhchev, G., Karadzhov, S., Valcheva, N., Vassileva, P., Ignatov, A., Angushev, I., Todorova, T., Angelcheva, M.. Results obtained with EVOagri technology to improve yield using filtered water in Africa, Tibet, Italy and Bulgaria. Plant Science Today, 10, 2, 2023, DOI:https://doi.org/10.14719/pst.2034, 137-143. SJR (Scopus Q3):0.211

22. Todorova TI, Parvanova PN, Boyadzhiev KP, Dimitrov MD, Chankova SG (2023) Genotype differences towards lead chloride harmful action. In: Chankova S, Danova K, Beltcheva M, Radeva G, Petrova V, Vassilev K (Eds) Actual problems of Ecology. BioRisk 20: 37–57. https://doi.org/10.3897/biorisk.20.97598 (SJR (Scopus):0.3 Q2)

23. Chankova SG, Yurina NP, Todorova TI, Parvanova PN (2023) Does overproduction of chaperone proteins favour the repair of DNA injuries induced by oxidative stress? (Mini review). In: Chankova S, Danova K, Beltcheva M, Radeva G, Petrova V, Vassilev K (Eds) Actual problems of Ecology. BioRisk 20: 7–22. https://doi.org/10.3897/biorisk.20.97569 (SJR (Scopus):0.3 Q2)

24. Todorova, T., Alexieva, I., Ostoich, P., Dimitrova, M., Boyadzhiev, K., Lyubomirova, V., Beltcheva, M.. Different Lead- and Cadmium-Induced Oxidative Stress Profiles in the Liver and Kidneys of Subchronically-Exposed Mice. ACTA ZOOLOGICA BULGARICA, 75, 3, 2023, 343-349. JCR-IF (Web of Science): 0.488.

25. Parvanova, P., Todorova, T., Sidjimova, B., Nikolova, M., Berkov, S., Chankova, S. 2024. Narcissus cv. Hawera leaves’ extract cleaves DNA in Chlamydomonas reinhardtii by inducing DSBs. Comptes rendus de l’Académie bulgare des Sciences, 77(3), 346-353. https://doi.org/10.7546/CRABS.2024.03.04 (SJR (Scopus):0.18 Q3; JCR-IF (Web of Science):0.3)

26. Todorova, T., Ivanova, I., Parvanova, P., Chankova, S. 2024. Clinopodium vulgare L. extract counteracts DNA damaging action of radiomimetic Zeocin accelerating DSBs rejoining in Saccharomyces cerevisiae, Comptes rendus de l'Académie bulgare des Sciences, 77(2), 196-203, https://doi.org/10.7546/CRABS.2024.02.04 (SJR (Scopus):0.18 Q3; JCR-IF (Web of Science):0.3)

27. Todorova, T., Boyadzhiev, K., Dimitrov, M., Parvanova, P.. Bee venom genotoxicity on Saccharomyces cerevisiae cells – The role of mitochondria and YAP1 transcription factor. Toxicology, 503, Elsevier, 2024, DOI:https://doi.org/10.1016/j.tox.2024.153768, (SJR (Scopus):0.84, JCR-IF (Web of Science):4.5 Q1)

Articles in journals without IF/SJR

28. Todorova, T., Bardarov, K., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S. (2015) Protective activity of different extracts of Clinopodium vulgare L., Proceedings - Seminar of Ecology - 2014 with international participation, pp. 98-101.ISBN:979-853-476-132-4

29. Todorova, T., Miteva, D., Chankova, S. (2016) How experimental design affects adaptive response in Saccharomyces cerevisiae , Proceedings - Seminar of Ecology - 2015 with international participation, pp. 167-170.ISBN:979-853-476-132-4

30. Todorova, T, Miteva, D, Radovanova, N, Ivanova, I, Chankova, S. DNA protection by Clinopodium vulgare against zeocin-induced double-strand breaks - role of genotype and experimental design. Proceedings Seminar of Ecology - 2016 with international participation, Farago, 2017, ISBN:979-853-476-132-4, 160-162

31. Radovanova, N, Ivanova, I, Todorova, T, Chankova, S. Does combined treatment with Clinopodium vulgare extract and zeocin protect nuclear DNA from zeocin-induced damages?. Proceedings Seminar of Ecology - 2016 with international participation, Farago, 2017, ISBN:979-853-476-132-4, 163-165

32. Parvanova, P., Todorova, T., Miteva, D., Mitrovska, Z., Chankova, S.. DNA susceptibility of Chlamydomonas reinhardtii and Saccharomyces cerevisiae to Nurelle D. Proceedings of 10th anniversary "Seminar of Ecology – 2017", with international participation, Farago, 2018, ISBN:979-853-476-132-4, 129-131.

33. Todorova, T, Parvanova, P, Mohafrash, SMM, Kostadinov, K, Dimitrov, M, Iliev Ivan, Mitrovska, Z, Mossa, ATH, Chankova, S. Nurelle D® bioactivity depending on the test system. Institute of Biodiversity and Ecosystem Research, 2019, ISBN:978-954-9746-45-7, 87-98

34. Todorova, T.,Parvanova, P.,Dimitrova, M.,Mitrovska, Z., Chankova, S.OPTIMIZATION OF CFGE FOR SACCHAROMYCES CEREVISIAE STRAIN WITH A WILD TYPE CELL WALL STRUCTURE, Farago, 2020, ISBN:978-619-206-153-1, 39-41.

35. Todorova, T., Dimitrov, M., Ignatov, I., Gluhchev, G., & Dinkov, G. (2020). Oxidal® Ameliorates the Ty1 Retrotransposition Induced by Methyl Methanesulfonate in Saccharomyces cerevisiae. Microbiology Research Journal International, 30(4), 34-42. https://doi.org/10.9734/mrji/2020/v30i430211

36. Стефка Чанкова, Теодора Тодорова, Мария Тодорова, Петя Първанова, Мария Йовкова (2020)Мутагенеза от околната среда - съвременно предизвикателство. Списание на БАН, бр. 2, 56-61.

37. Dimitrova, M., Dimitrov, V., Todorova, T. THE ROLE OF THE INTERACTIVE BINARY LESSON IN TEACHING BULGARIAN AS A SECOND LANGUAGE. BULGARSKI EZIK I LITERATURA-BULGARIAN LANGUAGE AND LITERATURE, 2021, 63(6), pp. 669-681. DOI:https://doi.org/10.53656/bel2021-6-7.bg/for

38. Dimitrova, M., Krasteva, H., Todorova, T. THEORY AND PRACTICE IN TEACHING BULGARIAN AS FOREIGN LANGUAGE IN THE FREELY CHOSEN DISCIPLINE "BULGARIAN FOR MEDICAL PURPOSES". Bulgarski Ezik i Literatura – Bulgarian Language and Literature, 64(3), 2022, pp. 292-306. DOI:https://doi.org/10.53656/bel2022-3-5-DK

39. Dimitrov, Z. P., Popova, T. P., Gotova, I. M., Ignatov , I., Todorova, T., Petrova, T. E., Huether, F. Determination of the Anti-inflammatory and Anti-microbial Activity of a Cosmetic Product Silver Stop® Cream. Journal of Pharmaceutical Research International, 35, 4, 2023, DOI:doi: 10.9734/jpri/2023/v35i47321, 32-43

Book chapters:

40. Димитрова, Маргарита, Тодорова, Теодора. Някои аспекти на успешната презентация на медицинска тема. Студио 18, 2020, ISBN:978-619-7249-67-5, 107, глава от книга

41. Тодорова, Т, Първанова, П, Йовкова, М, Димитрова, М, Чанкова, С. Афицидна активност, генотоксичен и мутагенен потенциал на етерично масло от бял риган. Биоцидни свойства на етерично масло от Origanum vulgare subsp. hirtum (Link) letsw. (гръцки, бял риган), Интел Ентранс, 2021, 41-58, глава от книга

42. Todorova, T.. Apricot (Prunus sect. armeniaca) kernels and usage in cancer studies. Ancient and Traditional Foods, Plants, Herbs and Spices in Human Health, CRC Press | Taylor & Francis Group, 2023, ISBN:978-1-032-19253-6, DOI:https://doi.org/10.1201/9781003260028-10, 10, 103-113

43. Chankova, S., Todorova, T., Parvanova, P.. Does the DNA Protective Capacity of Lilium candidum Extract and its Components Depend on the Experimental Design?. Cutting Edge Research in Biology, 3, BP International, 2023, ISBN:978-81-961092-6-4, DOI:https://doi.org/10.9734/bpi/cerb/v3/17472D, 90-103

Monograph:

Тодорова, Т. Saccharomyces cerevisiae – модел за изследване на ефекта на ниските температури и окислителния стрес. Викер, 2022, София, България; ISBN:978-954-92406-2-7; COBISS.BG-ID - 54976008

Учебници и учебни помагала:
1. Димитрова, М., Т. Тодорова, Д. Мирчев, Б. Айвазов, В. Димитров, М. Георгиева. Специализиран български език за чуждестранни студенти по медицина, второ преработено издание, Пловдив: Студио 18, 2019 г. ISBN 978-619-7249-44-6

2. Димитрова, М., Теодора Тодорова, Димитър Мирчев, Благой Айвазов, Васил Димитров, Мария Георгиева. Специализиран български език за чуждестранни студенти по медицина, трето преработено издание, Пловдив: Студио 18, 2019. ISBN 978-619-7249-57-6

3. Димитрова, М., Т. Тодорова, В. Димитров. Специализиран български език за чуждестранни студенти, второ преработено издание, Пловдив: Студио 18, 2019 г. ISBN 978-619-7249-55-2

4. Димитрова, М., Т. Тодорова, Д. Мирчев, Бл. Айвазов, В. Димитров, М. Георгиева. Специализиран български език за чуждестранни студенти по медицина, четвърто преработено издание. Пловдив: Студио 18, 2021. ISBN 978-619-7249-73-6

5. Димитров, В., Юл Кичукова, Бл. Айвазов, В. Александров, М. Орбецова, М. Атанасова, Ст. Вълканов, Н. Иванова, Ф. Щерев, Ал Торосян, Ст. Марков, Т. Тодорова. Учебно помагало по български език за чуждестранни студенти, Пловдив: Студио 18, 2021. ISBN 978-619-7249-72-9

6. Димитрова, М, Иванова, Н., Тодорова, Т. Учебно помагало по български език за работа с чужденци кардиолози. Студио 18, 2022, ISBN:978-619-7249-88-0

7. Димитрова, М, Кичукова, Ю., Айвазов, Б., Тодорова, Т. Учебно помагало с материали за изпит по български език на чуждестранни студенти по медицина. Студио 18, 2022, ISBN:978-619-7249-89-7

8. Димитрова, М, Кичукова, Ю., Айвазов, Б., Тодорова, Т. Учебно помагало с материали за изпит по български език на чуждестранни студенти по медицина. Студио 18, 2023, ISBN: 978-619-7751-02-4

9. Димитрова, М, Кичукова, Ю., Айвазов, Б., Тодорова, Т. Учебно помагало към учебниците "Български език за чужденци, първа част" и "Български език за чужденци, втора част". Студио 18, 2023, ISBN:978-619-7751-01-7

Affiliation

Department
Ecosystem Research, Environmental Risk Assessment and Conservation Biology
Division
Environmental Mutagenesis

History

Member for
11 years 1 week