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Teodora Todorova

Teodora Todorova's picture

Personal information

Contacts

Institute of Biodiversity and Ecosystem Research
2 Yurii Gagarin Street
1113 Sofia
Bulgaria
e-mail: tedi_todorova@yahoo.com
Teodora Todorova on ResearchGate
https://orcid.org/0000-0003-1075-4482
Scopus Author ID: 55811219600
Web of Science ResearcherID: H-5169-2015
Loop profile: 278013

Curriculum vitae

Date and place of birth: 28th December 1986, Montana, Bulgaria

Education:
2009- BSc in Molecular Biology, Sofia University "St.Kliment Ohridski"
2011- MSc in Genetics, Sofia University "St.Kliment Ohridski"
2015 - PhD in Genetics, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences

Project participation
2009 - 2011 - Participant “Mutagenic effect of low temperatures on nuclear DNA of eukaryotic cells”, funded by National Science Fund of Sofia University “St. Kliment Ohridski”, Project leader: Dr. Margarita Pesheva, Faculty of Biology, Sofia University “St. Kliment Ohridski”, Bulgaria

2012 - 2014 - Participant „Evaluation of DNA protective potential of biologically active natural compounds against DNA damaging factors", funded by National Science Fund,(DNTS01/1/Slovakia) Project leader: prof. Stephka Chankova, Institute of Biodiversity and Ecosystem Research - BAS, Bulgaria

2016 - 2019 - Coordinator “Strategies for overcoming the genetic risk of anthropogenic pollution with organophosphorus pesticides”, Bilateral agreement between Bulgarian Academy of Sciences and National Research Center, Egypt

2016 - Coordinator “DNA protective potential in vitro cultivated Clinopodium vulgare L. plant extracts”, funded by Ministry of Education and Science, Bulgaria

2018 – 2020 – Participant “Saccharomyces cerevisiae quiescence – smart model for toxicological and stress response research”, funded by National Science Fund - Ministry of Education and Science; Project coordinator: Assoc. Prof. Ventsislava Petrova, PhD.

2019 - 2022 Coordinator “Preparation and characterization of eco-friendly green and nanopesticides for spider mites and aphids control” Bilateral agreement between Bulgarian Academy of Sciences and National Research Center, Egypt

Membership:
The Genetics Society of America – since 11/2015 – 12/2017

National Postdoctoral Association – since 11/2015 – 12/2016

Union of Scientists in Bulgaria – Section Biology – since 09/2013 - present

Participation in national/international meetings

1.Todorova T., 2008, “Manganese and Parkinson’s disease”, 3rd workshop on biological activity of metals and metal compounds, 19-20 November, 2008, Bulgarian Academy of Sciences, Sofia, Bulgaria.

2.Georgieva M., Todorova T., 2008, “Chromium and cancer”, 3rd workshop on biological activity of metals and metal compounds, 19-20 November, 2008, Bulgarian Academy of Sciences, Sofia, Bulgaria.

3.Todorova T., 2008 “Abelson murine leukemia virus”, Seminar on virus-induced cancerogenesis, Bulgarian Academy of Sciences, Sofia, Bulgaria.

4.Todorova T., 2008 “Simian Gammaherpesviruses”, Seminar on virus-induced cancerogenesis, Bulgarian Academy of Sciences, Sofia, Bulgaria.

5.Todorova T., Popova T., Alexandrova R., Georgieva M., Farràs. P, Viñas, C., 2009, “Newly synthesized metallacarboranes: Investigations on antimicrobial activity and effect on viability of cultured nontumor cells”, International Medical Students’ Research Congress 2009, 8-10 May, 2009, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

6.Georgieva M., Popova T., Alexandrova R., Todorova T., Grozav M., Crisan M., Simu G., Grad M., 2009, “Investigations on antimicrobial activity in vitro of some sodium salts of 4,4’- diaminostilben-2,2’- disulfonic acid and compounds of para- substituted benzoic acids with morpholine”, International Medical Students’ Research Congress 2009, 8-10 May, 2009, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.

7.Todorova T., M. Georgieva, 2009, “Zinc fingers- role in restriction enzymes and gene therapy”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

8.Todorova T., M. Georgieva, 2009, “Silver and its usage in wound treatment”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

9.R. Alexandrova, M. Georgieva, T. Todorova, D. Culita, G. Marinescu, L. Patron, 2009, “Let us remember zinc”, 4rd workshop on biological activity of metals and metal compounds, 24-25 November, 2009, Bulgarian Academy of Sciences, Sofia, Bulgaria.

10.Todorova T., 2010, “ Yeasts as a model system”, Workshop on experimental models and methods in biomedical researches, 16-17 March, 2010, Bulgarian Academy of Sciences, Sofia, Bulgaria

11.Todorova T., R. Stamenova , 2010, Cryopreservation causes replication fork stalling and activates the S- phase checkpoints in yeast Saccharomyces cerevisiae” 3rd Pan Arab Human Genetics Conference, Dubai, UAE

12.Todorova T., R. Stamenova, M. Pesheva, 2010, “ Microsatellite DNA- indicator for mutations caused by low temperatures”, Младежка научна конференция „ Климентови дни”, Биологически факултет, София, България

13.Todorova T., M. Pesheva, 2011, “Mutagenic effect of low temperatures on nuclear DNA in yeast Saccharomyces cerevisiae”, Bulgarian Academy of Sciences, Sofia, Bulgaria

14.Todorova T., M. Pesheva. 2012. Mutagenic effect of freezing on nuclear DNA of Saccharomyces cerevisiae. СУБ, Април 2012

15.Todorova T., M. Pesheva, S. Chankova. 2012. Antioxidant and anticarcinogenic effect of Papaver rhoeas L. extract on test- system Saccharomyces cerevisiae. 4th Congress of Ecologists of the Republic of Macedonia. Октомври 2012

16.Mahmud A., T. Todorova, S. Chankova. 2012. Biological effect of polluted soil samples on green alga Chlamydomonas reinhardtii. 4th Congress of Ecologists of the Republic of Macedonia. Октомври 2012

17.Todorova T., M. Pesheva, S. Chankova. 2013. Antimutagenic effect of Papaver rhoeas L. extract on test- system Saccharomyces cerevisiae - „Seminar of Ecology – 2013“, 25–26 April, Sofia

18. A. Mahmud, T. Todorova, Z. Mitrovska, S. Chankova. 2013. Impact of polluted soils on DNA and HSP70B of Chlamydomonas reinhardtii- „Seminar of Ecology – 2013“, 25–26 April, Sofia

19.Todorova T., Daniela Miteva, Ventzislav Bardarov, Krum Bardarov, Atanas Atanassov, Stephka Chankova (2014) Protective activity of different extracts of Clinopodium vulgare L., Seminar of Ecology with international participation - 2014, 24-25 April 2014, Sofia, Bulgaria.

20.Bardarov V., S. Konstantinov, K. Bardarov, T. Todorova, St. Chankova, M. Shishinjova and A. Atanasov (2014) Medical plants a case study on Clinopodium vulgare L., The 8th Meeting with International Participation TOGETHER IN CANCER CONTROL:IMMUNOLOGY, VIRISES, NATURAL PRODUCTS, 24-25 October 2014, Pleven, Bulgaria.

21.Todorova, T., Miteva, D., Pesheva, M., Chankova, S. (2015) Protective activity of Clinopodium vulgare L. leaves on Saccharomyces cerevisiae nuclear DNA, 2nd National Food Conference with international participation, 20-21 March, 2015, Sofia, Bulgaria.

22.Todorova, T., Miteva, D., Pesheva, M., Chankova, S. (2015) DNA double strand breaks repair capacity in yeast Saccharomyces cerevisiae after zeocin treatment, Seminar of Ecology with international participation - 2015, 23-24 April 2015, Sofia, Bulgaria.

23. Todorova, T., Miteva, D., Radovanova, N., Ivanova, I., Chankova, S. (2016) Role of genotype and experimental design for Saccharomyces cerevisiae DNA protection against zeocin-induced double-strand breaks by Clinopodium vulgare, Seminar of Ecology with international participation - 2016, 21-22 April 2016, Sofia, Bulgaria.

24. Radovanova, N., Ivanova, I., Todorova, T., Chankova, S. (2016)Does combined treatment with Clinopodium vulgare extract and zeocin protect nuclear DNA from zeocin-induced damages?, Seminar of Ecology with international participation - 2016, 21-22 April 2016, Sofia, Bulgaria.

25. Parvanova P., Todorova T., Miteva D., Mitrovska Zh., Chankova S..
DNA SUSCEPTIBILITY OF CHLAMYDOMONAS REINHARDTII AND SACCHAROMYCES CEREVISIAE TO NURELLE D Seminar of Ecology - 2017 with international participation, 27-28 April, 2017, Sofia, Bulgaria.

26. Todorova, T., Parvanova, P., Mossa, AT., Kostadinov, K., Dimitrov, M., Iliev, I., Mitrovska, Zh., Angelova T., Chankova, S. (2018) Nurelle D bioactivity depending on the test system, 11th Annual Seminar of Ecology – 2018 with international participation, 26 – 27 April 2018, Sofia, Bulgaria.

27. Todorova T, Parvanova P, Dimitrova M, Mitrovska Zh, Chankova S. (2019) Optimization of CFGE for Saccharomyces cerevisiae strain with a wild type cell wall structure, International Seminar of Ecology – 2019”, 18 - 19 April 2019, Sofia, Bulgaria.

28. Todorova T, Chankova S. (2019)Saccharomyces cerevisiae - a suitable model for environmental studies, The 1st NRC-Grenoble INP International Conference on Science and Sustainable Development,16 - 18 September 2019, Cairo, Egypt - Keynote speaker

29. Parvanova P., Dimitrova M., Yovkova M., Todorova T., Miteva D., Mitrovska Zh.,Chankova S. (2019) Comparative analysis of the biological activity of natural and chemical compounds on a battery of test systems, The 1st NRC-Grenoble INP International Conference on Science and Sustainable Development,16 - 18 September 2019, Cairo, Egypt

30. Мария Димитрова, Теодора Тодорова, Мария Йовкова, Петя Първанова, Красимир Бояджиев, Стефка Чанкова. Сравнителен анализ на антиоксидантната активност на растителни екстракти с различен произход , Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад

31.Теодора Тодорова, Петя Първанова, Мария Димитрова, Мария Йовкова, Стефка Чанкова (2019) ДНК “Topology“ тест – подходящ метод за определяне на антиоксидантна и ДНК защитна активност на природни продукти с растителен произход , Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад - получена награда за най-добър доклад на млад учен

32. Стефка Чанкова-Петрова, Т. Тодорова, М. Димитрова, П. Първанова, Д. Митева, Е. Димова, А. Айдън, Ж. Митровска. М. Йовкова (2019) Мутагенеза от околната среда - проблем на съвремието ни, Национална научна конференция „75 Години съюз на учените в България – В полза на науката и образованието“ , 26–28 септември 2019, МДУ „Фредерик Жолио-Кюри“, к. к. „Св. св. Константин и Елена“ - устен доклад

33. Тодорова, Т., Първанова, П., Димитрова, М., Йонкова, И., Кръстева, И., Шкондров, А., Митровска, Ж., Кожухарова, Е., Чанкова, С.. Дали екстракт от плодове на Amorpha fruticosa проявява генотоксичен и мутагенен ефект върху Saccharomyces cerevisiae или не? 7th Congress of pharmacy with international participation; Borovets, Bulgaria; 21.11.2019 - 24.11.2019 - постер

34. Yovkova, M., Parvanova, P., Dimitrova, M., Todorova, T., Chankova, S..
Natural products with potential aphicidal effect, Четиринадесета Работна среща „БИОЛОГИЧНА АКТИВНОСТ НА МЕТАЛИ, СИНТЕТИЧНИ СЪЕДИНЕНИЯ И ПРИРОДНИ ПРОДУКТИ”; София, България; 02.12.2019 - 04.12.2019 (Доклад)

35.Zidarova, E., Parvanova, P., Dimitrova, M., Dronchev, G, Todorova, T., Dimitrov, M, Yovkova, M., Chankova, S.Different response of two model systems to the action of essential oils with plants origin, Четиринадесета Работна среща „БИОЛОГИЧНА АКТИВНОСТ НА МЕТАЛИ, СИНТЕТИЧНИ СЪЕДИНЕНИЯ И ПРИРОДНИ ПРОДУКТИ”; София, България; 02.12.2019 - 04.12.2019 (Доклад)

36.Boyadzhiev, K., Dimitrov, M, Blazhev, G, Todorova, T., Chankova, S..
Genotoxic effect of bee venom on Saccharomyces cerevisiae; Четиринадесета Работна среща „БИОЛОГИЧНА АКТИВНОСТ НА МЕТАЛИ, СИНТЕТИЧНИ СЪЕДИНЕНИЯ И ПРИРОДНИ ПРОДУКТИ”; София, България; 02.12.2019 - 04.12.2019 (Доклад)

37.Parvanova, P., Todorova, T., Çavuş, H., Yovkova, M., Dimitrova, M., Boyadzhiev, K., Dimitrov, M, Chankova, S., Genotoxic and mutagenic potential of chlorpyrifos on Sacchromyces cerevisiae and Chlamydomonas reinhardtii Четиринадесета Работна среща „БИОЛОГИЧНА АКТИВНОСТ НА МЕТАЛИ, СИНТЕТИЧНИ СЪЕДИНЕНИЯ И ПРИРОДНИ ПРОДУКТИ”; София, България; 02.12.2019 - 04.12.2019 (Доклад)

38. Todorova T., Parvanova P., Çavuş H., Yovkova M., Dimitrova M., Mossa AT, Boyadzhiev K., Dimitrov M., Chankova S., Set of tests for chlorpyrifos toxicity screening, "International Seminar of Ecology – 2020”, 23 - 24 April 2020, Online, Sofia, Bulgaria.

39. Miteva D., Todorova T., Chankova S., How Chlorella Species respond to UV-B induced stress,"International Seminar of Ecology – 2020”, 23 - 24 April 2020, Online, Sofia, Bulgaria.

Teaching
2015 - 10 hours - Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2018 - 30 hours - Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria
2019 - 30 hours - Faculty of Biology, Sofia University "Saint Kliment Ohridski", Sofia, Bulgaria

Supervising master students

1. Iviyana Ivanova – 2016, M. Sc. in Microbiology, Thesis title: “DNA protective potential of Clinopodium vulgare L. extract and role of experimental design”

2. Kostadin Kostadinov – 2017, M. Sc. in Gene and Cellular engineering, Thesis title: “Study of the promutagenic and procarcinogenic potential of the pesticide Nurelle D”

3. Georgi Blazhev - 2020, M.Sc. in Gene and Cellular engineering, Thesis title: "The role of genotype and experimental design for the induction of adaptive response to Zeocin in yeast Saccharomyces cerevisiae"

Research interests

- Saccharomyces cerevisiae
- antimutagenesis, anticarcinogenesis
- mechanisms of induction and repair of DSBs
- Ty1 retrotransposition
- Adaptive response
- Natural products
- Microsatellite DNA
- Genome stability
- Protein remodeling
- Oxidative stress

Publications

1. Todorova, T., Pesheva, M., Stamenova, R., Dimitrov, M., Venkov, P, 2012, Mutagenic effect of freezing on nuclear DNA of Saccharomyces cerevisiae. Yeast, 29, 191–199. doi: 10.1002/yea.2901. (IF=1.955;Q1)

2. Chankova, S., Todorova, T., Parvanova, P., Miteva, D., Mitrovska, Z., Angelova, O., Imreova, P., Mucaji, P., 2013, Kaempferol and jatropham: are they protective or detrimental for Chlamydomonas reinhardtii? Comptes rendus de I`Académie bulgare des Sciences, 66(8), 1121- 1128. (IF=0.211; Q2)

3. Todorova, T., Miteva, D., Chankova, S., 2015, DNA damaging effect of zeocin and methyl methanesulfonate in Saccharomyces cerevisiae measured by CFGE, Comptes rendus de I`Académie bulgare des Sciences, 68(1), 71-78. (IF=0.198; Q2)

4. Todorova, T., Pesheva, M., Gregan, F., Chankova, S., 2015, Antioxidant, antimutagenic and anticarcinogenic effects of Papaver rhoeas L. extract on Saccharomyces cerevisiae, Journal of Medicinal Food, 18(4): 460-467. doi:10.1089/jmf.2014.0050 (IF=1.622; Q2)

5. Bardarov, K.,Todorova, T., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S.(2016) Preliminary screening for study of the chemical composition of Clinopodium vulgare L. water extract, Comptes rendus de I`Académie bulgare des Sciences, 69(6), 717-724 (IF=0.233; Q2)

6. Todorova, T., Bardarov, K., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S.(2016) DNA protective activities of Clinopodium vulgare L. extracts, Comptes rendus de I`Académie bulgare des Sciences, 69(8), 1019-1024 (IF=0.233; Q2)

7. Todorova, A., Pesheva, M., Iliev, I., Bardarov, K., Todorova, T. Antimutagenic, Antirecombinogenic, and Antitumor Effect of Amygdalin in a Yeast Cell–Based Test and Mammalian Cell Lines, Journal of Medicinal Food, 2017, 20(4): 360-366. doi:10.1089/jmf.2016.0108 (IF=1.844; Q2)

8. Todorova, T, Miteva, D., Chankova, S. DNA susceptibility of Saccharomyces cerevisiae to Zeocin depends on the growth phase, International Microbiology, 2019, 22, 419–428, (IF=1.256; Q3) https://doi.org/10.1007/s10123-019-00065-5

9.Dimitrova, M, Miteva, D, Todorova, T, Parvanova, P, Yovkova, M, Dimitrov, M., Chankova, S. DNA-REPAIR DEFICIENT STRAINS CHLAMYDOMONAS REINHARDTII AS GOOD TOOLS FOR ENVIRONMENTAL TOXICOLOGY. Comptes rendus de l’Académie bulgare des Sciences, in press, 2020, JCR-IF (Web of Science):0.343; Q2 (Scopus)

10. Miteva, D, Todorova, T, Chankova, S. How Chlorella species isolated from contrasting habitats respond to UV-B induced stress?. Ecologia Balkanica, in press, 2020, SJR (Scopus):0.13

11. Todorova, T, Parvanova, P, Çavuş, H, Yovkova, M, Dimitrova, M, Mohafrash, S, Mossa, AT, Boyadzhiev, K, Dimitrov, M., Chankova, S. Set of tests for chlorpyrifos toxicity screening. Ecologia Balkanica, in press, 2020, SJR (Scopus):0.13

Articles in journals without IF

12. Todorova, T., Bardarov, K., Miteva, D., Bardarov, V., Atanassov, A., Chankova, S. (2015) Protective activity of different extracts of Clinopodium vulgare L., Proceedings - Seminar of Ecology - 2014 with international participation, pp. 98-101.ISBN:979-853-476-132-4

13. Todorova, T., Miteva, D., Chankova, S. (2016) How experimental design affects adaptive response in Saccharomyces cerevisiae , Proceedings - Seminar of Ecology - 2015 with international participation, pp. 167-170.ISBN:979-853-476-132-4

14. Todorova, T, Miteva, D, Radovanova, N, Ivanova, I, Chankova, S. DNA protection by Clinopodium vulgare against zeocin-induced double-strand breaks - role of genotype and experimental design. Proceedings Seminar of Ecology - 2016 with international participation, Farago, 2017, ISBN:979-853-476-132-4, 160-162

15. Radovanova, N, Ivanova, I, Todorova, T, Chankova, S. Does combined treatment with Clinopodium vulgare extract and zeocin protect nuclear DNA from zeocin-induced damages?. Proceedings Seminar of Ecology - 2016 with international participation, Farago, 2017, ISBN:979-853-476-132-4, 163-165

16. Parvanova, P., Todorova, T., Miteva, D., Mitrovska, Z., Chankova, S.. DNA susceptibility of Chlamydomonas reinhardtii and Saccharomyces cerevisiae to Nurelle D. Proceedings of 10th anniversary "Seminar of Ecology – 2017", with international participation, Farago, 2018, ISBN:979-853-476-132-4, 129-131.

17. Todorova, T, Parvanova, P, Mohafrash, SMM, Kostadinov, K, Dimitrov, M, Iliev Ivan, Mitrovska, Z, Mossa, ATH, Chankova, S. Nurelle D® bioactivity depending on the test system. Institute of Biodiversity and Ecosystem Research, 2019, ISBN:978-954-9746-45-7, 87-98

18. Todorova, T.,Parvanova, P.,Dimitrova, M.,Mitrovska, Z., Chankova, S.OPTIMIZATION OF CFGE FOR SACCHAROMYCES CEREVISIAE STRAIN WITH A WILD TYPE CELL WALL STRUCTURE, Farago, 2020, ISBN:978-619-206-153-1, 39-41.

19. Todorova, T., Dimitrov, M., Ignatov, I., Gluhchev, G., & Dinkov, G. (2020). Oxidal® Ameliorates the Ty1 Retrotransposition Induced by Methyl Methanesulfonate in Saccharomyces cerevisiae. Microbiology Research Journal International, 30(4), 34-42. https://doi.org/10.9734/mrji/2020/v30i430211

20. Стефка Чанкова, Теодора Тодорова, Мария Тодорова, Петя Първанова, Мария Йовкова (2020)Мутагенеза от околната среда - съвременно предизвикателство. Списание на БАН, бр. 2, 56-61.

Affiliation

Department
Ecosystem Research, Environmental Risk Assessment and Conservation Biology
Division
Environmental Mutagenesis

History

Member for
7 years 25 weeks