Skip to Content

Nadezhda Todorova

снимка на Nadezhda Todorova

Personal information

Contacts

Institute of Biodiversity and Ecosystem Research (IBER)
Bulgarian Academy of Sciences

2, Yuri Gagarin Street
Sofia 1113, Bulgaria
Phone: 00359 28717195 (via operator); 00359 887125076
nadeshda@abv.bg; nadeshdahr@gmail.com

Curriculum vitae

- Education

2002: MSc in Biotechnological processes, Department of Biochemistry, Faculty of Biology, Sofia University “St. Kliment Okhridski”; Thesis: Characterization of recombinant mutants of the globular fragment of C1q B-chain component of the complement system

2010: PhD in Ecology, Central Laboratory of General Ecology, Bulgarian Academy of Sciences; Thesis: Structure and biodegradive potential of bacterial communities, living in oil polluted coastal marine sediments

- Employment:

2003 - 2010: Research Fellow in Molecular Genetics, Central Laboratory of General Ecology, BAS, Department of Functional ecology, Marine ecology workgroup.

2010 - present: Senior Assist. Prof., Division of Biomonitoring and Ecological Risk Assessment, Institute of Biodiversity and Ecosystem Research, BAS.

- International experience:

2005-2006: Exchange visit in Institute of Microbiology-ASCR, Prague, Czech Republic, Xenobiotic biodegradation Workgroup; Participant in 6FP project BIOTOOL: Biological procedures for diagnosing the status and predicting evolution of polluted environments.

2008: PhD course “Biological sequence analysis”, Center for Biological Sequence Analysis (CBS) and Technical University, Denmark.

2011: Exchange visit in University of Vienna, Austria, Department of Environmental Microbiology; Analysis of complex microbial communities and studies on evolution, diversity and function of environmental microorganisms involved in biogeochemical cycles.

2013: Computational Molecular Evolution, Technical University, Denmark (Corsera Certificate).

2014: Qualification in a high-technology science center in Europe (Project BG051PO001-3.3.05-0001 Science and Business), University of Vienna, Austria, Department of Environmental Microbiology; Molecular techniques to characterize bacterial communities in marine sediments, populated with Zostera sp. (real-time PCR, CARD-FISH of dsrAB genes).

Research interests

Research interests
- Xenobiotics and ecotoxicology

Experimental methods
- Microbial ecology
- Molecular techniques as an assessment tool of ecological status
- Xenobiotics in the environment (soil, marine sediments)
- Microbial communities structure
- Xenobiotic-degradive bacterial pathways (Glyphosate, oil)

Computational methods
- Molecular modelling
- Ecology and biomonitoring of model prokaryotic systems
- Ecotoxicology (molecular level)
- Autoimmune diseases, molecular approach and modelling

Publications

Selected publications:

- Experimental methods

Todorova N., R. Mironova, V. Karamfilov. 2014. Comparative molecular analysis of bacterial communities inhabiting pristine and polluted with polycyclic aromatic hydrocarbons Black Sea coastal sediments. Marine Pollution Bulletin, Vol. 83: 231-240. http://dx.doi.org/10.1016/j.marpolbul.2014.03.047

Todorova, N.H. , G. Radeva and V. Karamfilov. 2012. Microbial diversity in Zostera sp. beds in south-western Black sea region analyzed by amplified ribosomal DNA restriction enzyme analysis (ARDRA). Biotechnology & Biotechnological Equipment (Special edition), Volume 26, No 1: 5-11. http://dx.doi.org/10.5504/50YRTIMB.2011.0002

Kopf A., M. Bicak, R. Kottmann, J. Schnetzer, I. Kostadinov, K. Lehmann, A. Fernandez-Guerra, C. Jeanthon, [...] N. Todorova, [...] J. A. Gilbert, N. Davies, D. Field, F. O. Gloeckner. 2015. The Ocean Sampling Day Consortium (Commentary). GigaScience. 4:27. DOI: 10.1186/s13742-015-0066-5

Caruso G., R. La Ferla, M. Azzaro, A. Zoppini, G. Marino, T. Petochi, C. Corinaldesi, M. Leonardi, R. Zaccone, S. Fonda Umani, [...] N. Todorova, E. Rastelli, S. Capello, M. I. Acquaviva, M. Narracci, R. De Angelis, P. DelNegro, M. Latini, R. Danovaro. 2015. Microbial assemblages for environmental quality assessment: knowledge, gaps and usefulness in the European Marine Strategy Framework Directive. Critical Reviews in Microbiology. DOI: 10.3109/1040841X.2015.1087380

Woerner S., S. Zecchin, J. Dan, N. H. Todorova, A. Loy, R. Conrad, M. Pester. 2016. Gypsum amendment to rice paddy soil stimulated bacteria involved in sulfur cycling but largely preserved the phylogenetic composition of the total bacterial community. Environmental Microbiology Reports. vol 8: 413-423 DOI: 10.1111/1758-2229.12413

Todorova, N., Stankov, A., Rangelov, M., Jovtchev, G.. Has Roundup an impact on microbial commiunities of agricultural soils?. Животна средина - Заштита - Зборници, COBISS.SR-ID 317216519, 2017, ISBN:978-86-83177-52-3, 109-114

Todorova N., Alyomov S., Chiotoroiu B.C., Fach B., Osadchaya T., Rangelov M., Salihoglu B., Vasilev V.. Black Sea Chapter 8. In: Carr H. (Ed.) World Seas: An Environmental Evaluation, Vol I: Europe, The Americas and West Africa, 2e, 1, Elsevier, 2018, ISBN:978-0-12-8050682, DOI:https://www.elsevier.com/books/world-seas-an-environmental-evaluation/sheppard/978-0-12-805068-2, 17, 209-226

Gateva, S., Stankov, A., Angelova, T., Todorova, N., Rangelov, M., Zlateva, B., Jovtchev, G.. Evaluation of toxic and genotoxic effects of roundup after direct and indirect treatment. International journal of ecosystems and ecology science (IJEES), 9, 3, 2019, ISSN:2224-4980, DOI:https://doi.org/10.31407/ijees9301, 409-416

- Computational methods

Rangelov, M., Todorova, N., Jovtchev, G.. CellRan: new conceptual program for ecosystem analysis and modelling. Животна средина - Заштита - Зборници, COBISS.SR-ID 317216519, 2017, ISBN:978-86-83177-52-3, 385-389

Todorov, P., Peneva P., Tchekalarova J., Rangelov, M., Georgieva S., Todorova N. Synthesis, characterization and anticonvulsant activity of new series of N-modified analogues of VV-Hemorphin-5 with aminophosphonate moiety. Amino Acids, Springer, 2019, DOI: 10.1007/s00726-019-02789-0

Tchekalarova J., Angelova V., Todorova N., Andreeva-Gateva P., Rangelov, M.. Evaluation of the anticonvulsant effect of novel melatonin derivatives in the intravenous pentylenetetrazol seizure test in mice. European Journal of Pharmacology, 863, 172684, Elsevier, 2019, DOI:10.1016/j.ejphar.2019.172684

Angelova V. T., Rangelov M., Todorova N., Dangalov M., Andreeva-Gateva P., Kondeva-Burdina M., Karabeliov V., Shivachev B., Tchekalarova J.. Discovery of novel indole-based aroylhydrazones as anticonvulsants: Pharmacophore-based design. Bioorganic Chemistry, Elsevier, 2019, DOI:https://doi.org/10.1016/j.bioorg.2019.103028

Ossowicz, P, Janus, E, Klebeko, J, Światek, E, Kardaleva, P, Taneva, S, Krachmarova, E, Rangelov, M, Todorova, N., Guncheva, M. Modulation of the binding affinity of naproxen to bovine serum albumin by conversion of the drug into amino acid ester salts. Journal of Molecular Liquids, Elsevier, 2020, DOI:https://doi.org/10.1016/j.molliq.2020.114283, SJR (Scopus):0.883

Litov, L., Petkov, P., Rangelov, M., Ilieva, N., Lilkova, E., Todorova, N., Krachmarova, E., Malinova, K., Gospodinov, A., Hristova, R., Ivanov, I., Nacheva, G.. Molecular Mechanism of the Anti-Inflammatory Action of Heparin. International Journal of Molecular Sciences, 22, MDPI, 2021, DOI:https://doi.org/10.3390/ijms221910730, 10730.

Todorova, N., Rangelov, M., Bogoeva, V., Stoyanova, V., Yordanova, A., Nikolova, G., Georgiev, H., Dimitrova, D., Mohedin, S., Stoyanova, K., Tsachevaa, I.. Anti-Idiotype scFv Localizes an Autoepitope in the Globular Domain of C1q. International Journal of Molecular Sciences, 22, MDPI, 2021, DOI:https://doi.org/10.3390/ijms22158288

Affiliation

Department
Ecosystem Research, Environmental Risk Assessment and Conservation Biology
Division
Biomonitoring and Ecological Risk Assessment

Хронология

Член от
9 години 29 седмици